Cosmetics Europe at EUROTOX 2017, Bratislava

The 53rd Congress of the European Societies of Toxicology will be held in Bratislava from 10-13 September 2017. The programme includes 30 symposia and workshops highlighting the novel findings in the field of toxicology and also features four poster sessions and five continuing education courses.

Specifically, for EUROTOX, Cosmetics Europe prepared a session titled New approaches to skin sensitisation safety assessment (Session 18), which will take place on Tuesday, 12 September, from 14h00-16h00.

This session will offer an overview of projects that the Cosmetics Europe Skin Bioavailability and Metabolism (Skin BM) Task Force (TF) and the Skin Tolerance (ST) TF run. Results from these projects exemplify how safety assessment for skin sensitization, as well as identification of possible systemic effects of topically applied chemicals, can follow the 21st century vision for toxicity testing.

The session will comprise the following presentations:

Progress in the validation and regulatory adoption of alternative approaches for skin sensitisation assessment
Silvia Casati 
European Commission, Joint Research Centre, Ispra, Italy

Impact of Cutaneous Bioavailability in Local Skin Toxicity: Preliminary results from Cosmetics Europe Skin Bioavailability and Metabolism Task Force 
Sebastien Gregoire et al.
L’Oreal Research & Innovation, Aulnay-sous-Bois, France

Skin penetration in silico modeling-improvement by using in vitro data 
Helga Rothe, et al.
Coty, Darmstadt, Germany; 2Procter and Gamble, Darmstadt, Germany; 

Cosmetics Europe’s skin sensitisation database 
Sebastian Hoffmann, et al.
SEH consulting + services, Paderborn, Germany

Skin sensitization testing strategy and safety assessment of topical ingredients: A case study
Dirk Petersohn, et al.
Henkel, Duesseldorf, Germany

Moreover, Catherine Mahony from Procter & Gamble, UK will run a continuous education course General principles of cosmetic safety evaluation: the industrial perspectives.

Cosmetics Europe will also present as many as 7 posters during EUROTOX:

Better understanding of bioavailability of cosmetic ingredients: Results from Cosmetics Europe skin bioavailability project; Andreas Schepky, Richard Cubberley, Helene Duplan, Joan Eilstein, Corie Ellison, Sebastien Grégoire, Nicky Hewitt, Carine Jacques-Jamin, Daniela Lange, Amy Roe, Helga Rothe, Martina Klaric

Cosmetics Europe assessment of non-animal approaches for predicting skin sensitization; Martina Klaric, Nathalie Alépée, Dave Allen, Takao Ashikaga, Warren Casey, Elodie Clouet, Magalie Cluzel, Aurelia Del Bufalo, Nikki Gellatly, Carsten Goebel, Sebastian Hoffmann, Petra Kern, Jochen Kuehnl, Karsten Mewes, Masaaki Miyazawa, Dirk Petersohn, Judy Strickland, Erwin Van Vliet, Dan Zang, Nicole Kleinstreuer

The importance of understanding physico-chemical properties of chemicals in the evaluation of serious eye damage/eye irritation: Cosmetic Europe analysis; Uwe Pfannenbecker, Els Adriaens, Nathalie Alépée, Daniel Bagley, Bertrand Desprez, Jalila Hibatallah, Karsten R. Mewes, Sala Àlvar, Pauline McNamee

Cosmetics Europe Analysis of the Robustness of Testing Strategies for UN GHS Classification for Serious Eye Damage/Eye Irritation of Chemicals; Nathalie Alépée, Els Adriaens, Daniel Bagley, Bertrand Desprez, Jalila Hibatallah, Karsten Mewes, Uwe Pfannenbecker, Àlvar Sala, Pauline McNamee

Cosmetics Europe eye programme: relevance to integrated approaches on testing and assessment for serious eye damage/ eye irritation; Bertrand Desprez, Nathalie Alépée, Els Adriaens, Daniel Bagley, Jalila Hibatallah, Karsten Mewes, Uwe Pfannenbecker, Àlvar Sala, Pauline McNamee

Cosmetics Europe systemic toxicity case studies; Bertrand Desprez, Dagmar Bury, Sarah Tozer, Martina Klaric, Matthew Dent, Detlef Keller, Gladys Ouédraogo, Richard Cubberley, Helene Duplan, Joan Eilstein, Corie Ellison, Sebastian Grégoire, Nicky Hewitt, Carine Jacques-Jamin, Daniela Lange, Amy Roe, Helga Rothe, Bas Blaauboer, Andreas Schepky, Catherine Mahony

In-vitro-only testing strategies for cosmetic ingredients: Utility of newly validated genotoxicity assays using human skin and fertilized hen’s eggs; Bertrand Desprez, Rolf Fautz, Sebastian Hoffmann, Nicola Hewitt, Paul Fowler, Kerstin Reisinger, Jochen Kuehnl, Gladys Ouédraogo, Julia Kenny, Stefan Pfuhler